node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FolE | HgdB-2 | PTH_1399 | PTH_0788 | GTP cyclohydrolase I. | benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB. | 0.510 |
FolE | NrdG | PTH_1399 | PTH_1400 | GTP cyclohydrolase I. | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.934 |
FolE | PTH_1398 | PTH_1399 | PTH_1398 | GTP cyclohydrolase I. | Hypothetical protein. | 0.755 |
FolE | PTH_1401 | PTH_1399 | PTH_1401 | GTP cyclohydrolase I. | Hypothetical protein; DUF366, Domain of unknown function (DUF366). Archaeal domain of unknown function. | 0.780 |
FolE | PTH_1403 | PTH_1399 | PTH_1403 | GTP cyclohydrolase I. | 6-pyruvoyl-tetrahydropterin synthase. | 0.997 |
FolE | SurE | PTH_1399 | PTH_1397 | GTP cyclohydrolase I. | Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.772 |
FolE | queC | PTH_1399 | PTH_1402 | GTP cyclohydrolase I. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.819 |
HgdB-2 | FolE | PTH_0788 | PTH_1399 | benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB. | GTP cyclohydrolase I. | 0.510 |
HgdB-2 | NrdG | PTH_0788 | PTH_1400 | benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB. | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.728 |
HgdB-2 | PTH_1401 | PTH_0788 | PTH_1401 | benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB. | Hypothetical protein; DUF366, Domain of unknown function (DUF366). Archaeal domain of unknown function. | 0.474 |
HgdB-2 | PTH_1403 | PTH_0788 | PTH_1403 | benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB. | 6-pyruvoyl-tetrahydropterin synthase. | 0.636 |
HgdB-2 | queC | PTH_0788 | PTH_1402 | benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.523 |
NrdG | FolE | PTH_1400 | PTH_1399 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | GTP cyclohydrolase I. | 0.934 |
NrdG | HgdB-2 | PTH_1400 | PTH_0788 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB. | 0.728 |
NrdG | PTH_1398 | PTH_1400 | PTH_1398 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Hypothetical protein. | 0.637 |
NrdG | PTH_1401 | PTH_1400 | PTH_1401 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Hypothetical protein; DUF366, Domain of unknown function (DUF366). Archaeal domain of unknown function. | 0.934 |
NrdG | PTH_1403 | PTH_1400 | PTH_1403 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 6-pyruvoyl-tetrahydropterin synthase. | 0.999 |
NrdG | SurE | PTH_1400 | PTH_1397 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.680 |
NrdG | queC | PTH_1400 | PTH_1402 | Organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Predicted PP-loop superfamily ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.998 |
PTH_1398 | FolE | PTH_1398 | PTH_1399 | Hypothetical protein. | GTP cyclohydrolase I. | 0.755 |