Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SelASelenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (470 aa)    
Predicted Functional Partners:
SelD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
 
  
 0.995
SelB
Selenocysteine-specific translation elongation factor.
  
 0.994
SerS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
     
 0.928
BisC-2
Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.738
SirA-3
Predicted redox protein; Regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
 
  
 0.711
PTH_1711
Hypothetical formate dehydrogenase; Containing partial COG3383, Uncharacterized anaerobic dehydrogenase.
 
  
 0.663
PurB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
      
 0.625
PTH_1426
Hypothetical protein.
       0.583
SirA-2
Predicted redox protein; Regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
 
  
 0.506
Kch
Kef-type K+ transport systems, predicted NAD-binding component.
   
    0.446
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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