STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CitB-3Response regulator; Containing a CheY-like receiver domain and an HTH DNA-binding domain. (217 aa)    
Predicted Functional Partners:
PTH_1443
Sensor protein DegS and signal transduction histidine kinase; DegS and COG3920.
 0.998
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
 
 0.965
BaeS-4
Signal transduction histidine kinase.
 
 0.937
PTH_2806
Hypothetical transcriptional regulator; Containing effector domain of the CAP family of transcription factors, Sigma-54 interaction domain and partial NapH (COG0348), Polyferredoxin.
  
 
 0.666
BaeS-2
Signal transduction histidine kinase.
 
 
 0.599
PTH_2869
Hypothetical signal transduction protein; Containing PAS domain and two FhlA (COG2203), FOG: GAF domain and partial AtoS (COG2202), FOG: PAS/PAC domain.
  
 
 0.591
PTH_1597
Hypothetical protein; Containing COG3852 NtrB, signal transduction histidine kinase and COG3706 PleD, response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 0.477
Fer
Ferredoxin.
       0.456
Sun
tRNA and rRNA cytosine-C5-methylases; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.436
PTH_2640
Containing FhlA (COG2203), FOG: GAF domain and partial COG4191, signal transduction histidine kinase regulating C4-dicarboxylate transport system.
  
 
 0.425
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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