Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CitB-3Response regulator; Containing a CheY-like receiver domain and an HTH DNA-binding domain. (217 aa)    
Predicted Functional Partners:
PTH_1443
Sensor protein DegS and signal transduction histidine kinase; DegS and COG3920.
 0.998
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
 
 0.947
BaeS-4
Signal transduction histidine kinase.
 
 
 0.928
PTH_2869
Hypothetical signal transduction protein; Containing PAS domain and two FhlA (COG2203), FOG: GAF domain and partial AtoS (COG2202), FOG: PAS/PAC domain.
  
 
 0.666
PTH_2806
Hypothetical transcriptional regulator; Containing effector domain of the CAP family of transcription factors, Sigma-54 interaction domain and partial NapH (COG0348), Polyferredoxin.
  
 
 0.601
BaeS-2
Signal transduction histidine kinase.
 
 
 0.473
Fer
Ferredoxin.
       0.456
GltB-2
Glutamate synthase domain 2.
      
 0.445
Flp
Flp pilus assembly protein, pilin Flp, pilin Flp.
  
    0.429
PTH_1597
Hypothetical protein; Containing COG3852 NtrB, signal transduction histidine kinase and COG3706 PleD, response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 0.405
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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