SdhB-2 protein (Pelotomaculum thermopropionicum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SdhB-2

Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (212 aa)

Predicted Functional Partners:

SdhA-3

0.995

SdhA-2

0.981

SdhC

0.973

SdhA

0.939

PTH_2647

0.901

NapF

0.878

PqqL

0.839

MmcD1

0.827

AcpP

0.820

MmcD2

0.814

Your Current Organism:

Pelotomaculum thermopropionicum

NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AcpP	NapF	PTH_1740	PTH_1473	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	Ferredoxin.	0.938
AcpP	PTH_2647	PTH_1740	PTH_2647	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	Hypothetical membrane protein; Containing partial NuoG (COG1034), NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G).	0.856
AcpP	PqqL	PTH_1740	PTH_1278	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.	0.829
AcpP	SdhA	PTH_1740	PTH_0239	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.585
AcpP	SdhA-2	PTH_1740	PTH_1017	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.585
AcpP	SdhA-3	PTH_1740	PTH_1491	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.585
AcpP	SdhB-2	PTH_1740	PTH_1490	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.820
MmcD1	MmcD2	PTH_1358	PTH_1359	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	succinyl-CoA synthetase, alpha subunit.	0.999
MmcD1	PTH_2647	PTH_1358	PTH_2647	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Hypothetical membrane protein; Containing partial NuoG (COG1034), NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G).	0.686
MmcD1	SdhA	PTH_1358	PTH_0239	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.702
MmcD1	SdhA-2	PTH_1358	PTH_1017	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.975
MmcD1	SdhA-3	PTH_1358	PTH_1491	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.791
MmcD1	SdhB-2	PTH_1358	PTH_1490	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.827
MmcD1	SdhC	PTH_1358	PTH_1016	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.989
MmcD2	MmcD1	PTH_1359	PTH_1358	succinyl-CoA synthetase, alpha subunit.	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.999
MmcD2	PTH_2647	PTH_1359	PTH_2647	succinyl-CoA synthetase, alpha subunit.	Hypothetical membrane protein; Containing partial NuoG (COG1034), NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G).	0.520
MmcD2	SdhA	PTH_1359	PTH_0239	succinyl-CoA synthetase, alpha subunit.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.655
MmcD2	SdhA-2	PTH_1359	PTH_1017	succinyl-CoA synthetase, alpha subunit.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.973
MmcD2	SdhA-3	PTH_1359	PTH_1491	succinyl-CoA synthetase, alpha subunit.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.768
MmcD2	SdhB-2	PTH_1359	PTH_1490	succinyl-CoA synthetase, alpha subunit.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.814

page 1 of 5

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About