SdhA-3 protein (Pelotomaculum thermopropionicum)

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SdhA-3

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (560 aa)

Predicted Functional Partners:

SdhB-2

0.999

SdhB

0.998

SdhC

0.995

MmcD1

0.977

MmcD2

0.974

MmcB

0.949

MmcC

0.949

NuoF-3

0.947

NadC

0.926

SdhA-2

0.913

Your Current Organism:

Pelotomaculum thermopropionicum

NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MmcB	MmcC	PTH_1356	PTH_1357	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	0.999
MmcB	MmcD1	PTH_1356	PTH_1358	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.698
MmcB	MmcD2	PTH_1356	PTH_1359	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	succinyl-CoA synthetase, alpha subunit.	0.425
MmcB	SdhA-2	PTH_1356	PTH_1017	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.949
MmcB	SdhA-3	PTH_1356	PTH_1491	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.949
MmcB	SdhB	PTH_1356	PTH_1018	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.945
MmcB	SdhB-2	PTH_1356	PTH_1490	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.945
MmcB	SdhC	PTH_1356	PTH_1016	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.951
MmcC	MmcB	PTH_1357	PTH_1356	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	0.999
MmcC	MmcD1	PTH_1357	PTH_1358	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.661
MmcC	MmcD2	PTH_1357	PTH_1359	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	succinyl-CoA synthetase, alpha subunit.	0.597
MmcC	SdhA-2	PTH_1357	PTH_1017	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.949
MmcC	SdhA-3	PTH_1357	PTH_1491	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.949
MmcC	SdhB	PTH_1357	PTH_1018	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.944
MmcC	SdhB-2	PTH_1357	PTH_1490	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.944
MmcC	SdhC	PTH_1357	PTH_1016	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.945
MmcD1	MmcB	PTH_1358	PTH_1356	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	0.698
MmcD1	MmcC	PTH_1358	PTH_1357	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	0.661
MmcD1	MmcD2	PTH_1358	PTH_1359	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	succinyl-CoA synthetase, alpha subunit.	0.999
MmcD1	NuoF-3	PTH_1358	PTH_2648	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit.	0.523

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