STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_1541Acyl CoA:acetate/3-ketoacid CoA transferase; Belongs to the 3-oxoacid CoA-transferase family. (520 aa)    
Predicted Functional Partners:
PTH_0490
acyl-CoA synthetase; NDP forming.
     
 0.947
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.947
PTH_1507
acyl-CoA synthetase; NDP forming.
     
 0.947
PTH_1750
acyl-CoA synthetase; NDP forming.
     
 0.947
Acs-2
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.947
PTH_2237
acyl-CoA synthetase; NDP forming.
     
 0.947
PaaJ
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.912
PTH_1577
acylCoA:acetate/3-ketoacidCoAtransferase; Belongs to the 3-oxoacid CoA-transferase family.
  
  
 
0.910
PTH_1584
Putative aldehyde/alcohol dehydrogenase; Containing PutA (COG1012), NAD-dependent aldehyde dehydrogenases and EutG (COG1454) alcohol dehydrogenase class IV; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.908
PTH_0512
Acyl CoA:acetate/3-ketoacid CoA transferase; Belongs to the 3-oxoacid CoA-transferase family.
  
  
 
0.903
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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