Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
PTH_1597Hypothetical protein; Containing COG3852 NtrB, signal transduction histidine kinase and COG3706 PleD, response regulator containing a CheY-like receiver domain and a GGDEF domain. (621 aa)    
Predicted Functional Partners:
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
 
 
0.980
BaeS-4
Signal transduction histidine kinase.
 
 
0.978
PTH_2869
Hypothetical signal transduction protein; Containing PAS domain and two FhlA (COG2203), FOG: GAF domain and partial AtoS (COG2202), FOG: PAS/PAC domain.
  
 
 0.931
CheR
Methylase of chemotaxis methyl-accepting proteins.
 
  
 0.930
PTH_0654
Hypothetical regulator protein; Containing LytS (COG3275), putative regulator of cell autolysis.
 
 
  
 0.905
PTH_2004
Hypothetical protein; Containing AtoS (COG2202), FOG: PAS/PAC domain, PAS domain, GGDEF, Diguanylate-cyclase (DGC) and HDc domain, Metal dependent phosphohydrolases with conserved 'HD' motif.
 
 0.900
PTH_2640
Containing FhlA (COG2203), FOG: GAF domain and partial COG4191, signal transduction histidine kinase regulating C4-dicarboxylate transport system.
 
 
0.854
PTH_1663
Hypothetical protein; Containing COG2202, AtoS, FOG: PAS/PAC domain, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain, and HDc, Metal dependent phosphohydrolases with conserved 'HD' motif.
 
 
 0.798
PTH_0717
Hypothetical protein.
  
 
 0.781
PTH_0047
Hypothetical signal transduction protein; Containing partial KdpD (COG2205).
 
 
0.758
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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