| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DdlA | FtsI-4 | PTH_1390 | PTH_1867 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | 0.839 |
| DdlA | MurC | PTH_1390 | PTH_1860 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.995 |
| DdlA | MurD | PTH_1390 | PTH_1863 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.933 |
| DdlA | MurE | PTH_1390 | PTH_1650 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl tripeptide synthase. | 0.635 |
| DdlA | MurF | PTH_1390 | PTH_1865 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.999 |
| DdlA | MurG | PTH_1390 | PTH_1264 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase. | 0.802 |
| DdlA | MurG-2 | PTH_1390 | PTH_1861 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.937 |
| DdlA | Rfe | PTH_1390 | PTH_1864 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.730 |
| FtsI-4 | DdlA | PTH_1867 | PTH_1390 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | 0.839 |
| FtsI-4 | MurC | PTH_1867 | PTH_1860 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.908 |
| FtsI-4 | MurD | PTH_1867 | PTH_1863 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.925 |
| FtsI-4 | MurE | PTH_1867 | PTH_1650 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylmuramyl tripeptide synthase. | 0.675 |
| FtsI-4 | MurF | PTH_1867 | PTH_1865 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.953 |
| FtsI-4 | MurG | PTH_1867 | PTH_1264 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase. | 0.439 |
| FtsI-4 | MurG-2 | PTH_1867 | PTH_1861 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.872 |
| FtsI-4 | Rfe | PTH_1867 | PTH_1864 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.914 |
| MurC | DdlA | PTH_1860 | PTH_1390 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | 0.995 |
| MurC | FtsI-4 | PTH_1860 | PTH_1867 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | 0.908 |
| MurC | MurD | PTH_1860 | PTH_1863 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.994 |
| MurC | MurE | PTH_1860 | PTH_1650 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylmuramyl tripeptide synthase. | 0.720 |