Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AcyPAcylphosphatases. (92 aa)    
Predicted Functional Partners:
Acs-2
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.904
PTH_0490
acyl-CoA synthetase; NDP forming.
     
  0.900
PTH_0512
Acyl CoA:acetate/3-ketoacid CoA transferase; Belongs to the 3-oxoacid CoA-transferase family.
     
  0.900
PTH_1507
acyl-CoA synthetase; NDP forming.
     
  0.900
PTH_1541
Acyl CoA:acetate/3-ketoacid CoA transferase; Belongs to the 3-oxoacid CoA-transferase family.
     
  0.900
PTH_1577
acylCoA:acetate/3-ketoacidCoAtransferase; Belongs to the 3-oxoacid CoA-transferase family.
     
  0.900
PTH_1750
acyl-CoA synthetase; NDP forming.
     
  0.900
PTH_1771
Acyl CoA:acetate/3-ketoacid CoA transferase; Belongs to the 3-oxoacid CoA-transferase family.
     
  0.900
PTH_2237
acyl-CoA synthetase; NDP forming.
     
  0.900
PTH_2429
Containing AtoD (COG1788), acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit and partial AtoA (COG2057), acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit.
     
  0.900
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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