Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTH_1663Hypothetical protein; Containing COG2202, AtoS, FOG: PAS/PAC domain, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain, and HDc, Metal dependent phosphohydrolases with conserved 'HD' motif. (638 aa)    
Predicted Functional Partners:
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
 
 0.976
BaeS-4
Signal transduction histidine kinase.
 
 0.969
PTH_2869
Hypothetical signal transduction protein; Containing PAS domain and two FhlA (COG2203), FOG: GAF domain and partial AtoS (COG2202), FOG: PAS/PAC domain.
  
 
 0.931
PTH_0666
Hypothetical signaling protein; Containing Rtn (COG2200), FOG: EAL domain.
 
 0.928
PTH_2004
Hypothetical protein; Containing AtoS (COG2202), FOG: PAS/PAC domain, PAS domain, GGDEF, Diguanylate-cyclase (DGC) and HDc domain, Metal dependent phosphohydrolases with conserved 'HD' motif.
  
 
 0.853
PTH_0546
Hypothetical protein; Containing COG2206, HD-GYP domain and FhlA (COG2203), FOG: GAF domain.
 
 
0.845
PTH_1597
Hypothetical protein; Containing COG3852 NtrB, signal transduction histidine kinase and COG3706 PleD, response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 0.798
PTH_1727
Hypothetical signaling protein; Containing FOG:GGDEF domain (COG2199) and ResE, FOG: HAMP domain (COG2770).
 
 
0.794
PTH_2757
Hypothetical membrane protein; Containing FOG (COG2199): GGDEF domain and FhlA (COG2203), FOG: GAF domain.
 
 
0.790
PTH_2868
Hypothetical protein.
  
 
 0.770
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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