| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ExbD | GyrA | PTH_2286 | PTH_0008 | Biopolymer transport protein. | Type IIA topoisomerase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.497 |
| ExbD | PhoU | PTH_2286 | PTH_1676 | Biopolymer transport protein. | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | 0.740 |
| ExbD | PstB | PTH_2286 | PTH_1677 | Biopolymer transport protein. | ABC-type phosphate transport system, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.740 |
| GltB-2 | PhoU | PTH_0734 | PTH_1676 | Glutamate synthase domain 2. | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | 0.604 |
| GltB-2 | PstB | PTH_0734 | PTH_1677 | Glutamate synthase domain 2. | ABC-type phosphate transport system, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.608 |
| GltB-2 | guaA | PTH_0734 | PTH_2551 | Glutamate synthase domain 2. | Hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.809 |
| GyrA | ExbD | PTH_0008 | PTH_2286 | Type IIA topoisomerase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Biopolymer transport protein. | 0.497 |
| GyrA | PhoU | PTH_0008 | PTH_1676 | Type IIA topoisomerase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | 0.598 |
| GyrA | PstB | PTH_0008 | PTH_1677 | Type IIA topoisomerase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | ABC-type phosphate transport system, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.571 |
| GyrA | guaA | PTH_0008 | PTH_2551 | Type IIA topoisomerase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.532 |
| ModC-2 | PstB | PTH_0677 | PTH_1677 | ABC-type molybdate transport system, ATPase component. | ABC-type phosphate transport system, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.592 |
| PhoU | ExbD | PTH_1676 | PTH_2286 | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | Biopolymer transport protein. | 0.740 |
| PhoU | GltB-2 | PTH_1676 | PTH_0734 | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | Glutamate synthase domain 2. | 0.604 |
| PhoU | GyrA | PTH_1676 | PTH_0008 | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | Type IIA topoisomerase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.598 |
| PhoU | PstA | PTH_1676 | PTH_1674 | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | ABC-type phosphate transport system, permease component. | 0.998 |
| PhoU | PstB | PTH_1676 | PTH_1677 | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | ABC-type phosphate transport system, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.999 |
| PhoU | PstC | PTH_1676 | PTH_1673 | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | ABC-type phosphate transport system, permease component; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.892 |
| PhoU | PstS | PTH_1676 | PTH_1671 | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | ABC-type phosphate transport system, permease component. | 0.922 |
| PstA | PhoU | PTH_1674 | PTH_1676 | ABC-type phosphate transport system, permease component. | Phosphate uptake regulator; Plays a role in the regulation of phosphate uptake. | 0.998 |
| PstA | PstB | PTH_1674 | PTH_1677 | ABC-type phosphate transport system, permease component. | ABC-type phosphate transport system, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.999 |