Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HypEHydrogenase maturation factor. (339 aa)    
Predicted Functional Partners:
HypD
Hydrogenase maturation factor.
 
 0.999
HypF
Hydrogenase maturation factor.
 
 
 0.998
HypC
Hydrogenase maturation factor.
 
 
 0.997
HyaD
Ni,Fe-hydrogenase maturation factor.
 
   
 0.971
HypB
Ni2+-binding GTPase; Involved in regulation of expression and maturation of urease and hydrogenase.
 
  
 0.885
HyaB
Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.872
HyaA
Ni,Fe-hydrogenase I small subunit.
 
   
 0.862
HybF
Zn finger protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.850
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.661
Mrp-3
ATPase; Involved in chromosome partitioning.
       0.625
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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