| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HyaA | HyaB | PTH_1701 | PTH_1702 | Ni,Fe-hydrogenase I small subunit. | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.999 |
| HyaA | HyaD | PTH_1701 | PTH_1700 | Ni,Fe-hydrogenase I small subunit. | Ni,Fe-hydrogenase maturation factor. | 0.903 |
| HyaA | HycB | PTH_1701 | PTH_0486 | Ni,Fe-hydrogenase I small subunit. | Fe-S-cluster; Containing hydrogenase components 2. | 0.924 |
| HyaA | HycB-2 | PTH_1701 | PTH_0609 | Ni,Fe-hydrogenase I small subunit. | Fe-S-cluster-containing hydrogenase components 2. | 0.924 |
| HyaA | HypB | PTH_1701 | PTH_2009 | Ni,Fe-hydrogenase I small subunit. | Ni2+-binding GTPase; Involved in regulation of expression and maturation of urease and hydrogenase. | 0.845 |
| HyaA | HypD | PTH_1701 | PTH_1698 | Ni,Fe-hydrogenase I small subunit. | Hydrogenase maturation factor. | 0.865 |
| HyaA | HypE | PTH_1701 | PTH_1699 | Ni,Fe-hydrogenase I small subunit. | Hydrogenase maturation factor. | 0.872 |
| HyaA | HypF | PTH_1701 | PTH_1696 | Ni,Fe-hydrogenase I small subunit. | Hydrogenase maturation factor. | 0.878 |
| HyaA | MmcM | PTH_1701 | PTH_1369 | Ni,Fe-hydrogenase I small subunit. | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.891 |
| HyaA | SdhC | PTH_1701 | PTH_1016 | Ni,Fe-hydrogenase I small subunit. | Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.789 |
| HyaB | HyaA | PTH_1702 | PTH_1701 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Ni,Fe-hydrogenase I small subunit. | 0.999 |
| HyaB | HyaD | PTH_1702 | PTH_1700 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Ni,Fe-hydrogenase maturation factor. | 0.935 |
| HyaB | HycB | PTH_1702 | PTH_0486 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Fe-S-cluster; Containing hydrogenase components 2. | 0.922 |
| HyaB | HycB-2 | PTH_1702 | PTH_0609 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Fe-S-cluster-containing hydrogenase components 2. | 0.922 |
| HyaB | HypB | PTH_1702 | PTH_2009 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Ni2+-binding GTPase; Involved in regulation of expression and maturation of urease and hydrogenase. | 0.866 |
| HyaB | HypD | PTH_1702 | PTH_1698 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Hydrogenase maturation factor. | 0.908 |
| HyaB | HypE | PTH_1702 | PTH_1699 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Hydrogenase maturation factor. | 0.887 |
| HyaB | HypF | PTH_1702 | PTH_1696 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Hydrogenase maturation factor. | 0.888 |
| HyaB | MmcM | PTH_1702 | PTH_1369 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.872 |
| HyaB | SdhC | PTH_1702 | PTH_1016 | Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.641 |