STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HyaBNi,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (482 aa)    
Predicted Functional Partners:
HyaA
Ni,Fe-hydrogenase I small subunit.
 
 0.999
HyaD
Ni,Fe-hydrogenase maturation factor.
 
 
 0.935
HycB
Fe-S-cluster; Containing hydrogenase components 2.
  
 
 0.922
HycB-2
Fe-S-cluster-containing hydrogenase components 2.
  
 
 0.922
HypD
Hydrogenase maturation factor.
 
 
 0.908
HybF
Zn finger protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.904
RnfC
Predicted NADH:ubiquinone oxidoreductase, subunit RnfC.
  
 
 0.888
HypF
Hydrogenase maturation factor.
 
 
 
 0.888
HypE
Hydrogenase maturation factor.
 
   
 0.887
PTH_2234
Uncharacterized conserved protein; Containing a ferredoxin-like domain.
  
 
 0.875
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.