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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NrfDPolysulphide reductase; NrfD perticipates in the transfer of electrons from quinone pool into the therminal components. (389 aa)    
Predicted Functional Partners:
HybA-2
Fe-S-cluster-containing hydrogenase components 1.
 
 0.972
HybA
Fe-S-cluster-containing hydrogenase components 1.
 
 0.930
HybA-3
Fe-S-cluster-containing hydrogenase components 1.
 
 0.927
HyaB
Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.772
BisC-2
Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.763
HyaA
Ni,Fe-hydrogenase I small subunit.
 
  
 0.760
TufB
GTPase - translation elongation factors; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.744
TufB-2
GTPase - translation elongation factors; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.744
HycB-2
Fe-S-cluster-containing hydrogenase components 2.
 
 
 0.744
PTH_1711
Hypothetical formate dehydrogenase; Containing partial COG3383, Uncharacterized anaerobic dehydrogenase.
 
 
 0.737
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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