| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ComEC-2 | ComFC | PTH_0857 | PTH_2756 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Predicted amidophosphoribosyltransferases. | 0.893 |
| ComEC-2 | PTH_1690 | PTH_0857 | PTH_1690 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Predicted ATPase; With chaperone activity. | 0.717 |
| ComEC-2 | PTH_1707 | PTH_0857 | PTH_1707 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | 0.500 |
| ComEC-2 | Smf | PTH_0857 | PTH_1245 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Predicted Rossmann fold nucleotide-binding protein; Involved in DNA uptake. | 0.917 |
| ComFC | ComEC-2 | PTH_2756 | PTH_0857 | Predicted amidophosphoribosyltransferases. | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | 0.893 |
| ComFC | PTH_1690 | PTH_2756 | PTH_1690 | Predicted amidophosphoribosyltransferases. | Predicted ATPase; With chaperone activity. | 0.816 |
| ComFC | PTH_1707 | PTH_2756 | PTH_1707 | Predicted amidophosphoribosyltransferases. | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | 0.583 |
| ComFC | Smf | PTH_2756 | PTH_1245 | Predicted amidophosphoribosyltransferases. | Predicted Rossmann fold nucleotide-binding protein; Involved in DNA uptake. | 0.915 |
| PTH_1690 | ComEC-2 | PTH_1690 | PTH_0857 | Predicted ATPase; With chaperone activity. | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | 0.717 |
| PTH_1690 | ComFC | PTH_1690 | PTH_2756 | Predicted ATPase; With chaperone activity. | Predicted amidophosphoribosyltransferases. | 0.816 |
| PTH_1690 | PTH_1707 | PTH_1690 | PTH_1707 | Predicted ATPase; With chaperone activity. | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | 0.826 |
| PTH_1690 | Smf | PTH_1690 | PTH_1245 | Predicted ATPase; With chaperone activity. | Predicted Rossmann fold nucleotide-binding protein; Involved in DNA uptake. | 0.937 |
| PTH_1707 | ComEC-2 | PTH_1707 | PTH_0857 | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | 0.500 |
| PTH_1707 | ComFC | PTH_1707 | PTH_2756 | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | Predicted amidophosphoribosyltransferases. | 0.583 |
| PTH_1707 | PTH_1690 | PTH_1707 | PTH_1690 | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | Predicted ATPase; With chaperone activity. | 0.826 |
| PTH_1707 | RnhB | PTH_1707 | PTH_1708 | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.817 |
| PTH_1707 | Smf | PTH_1707 | PTH_1245 | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | Predicted Rossmann fold nucleotide-binding protein; Involved in DNA uptake. | 0.740 |
| PTH_1707 | TatA | PTH_1707 | PTH_1709 | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | Sec-independent protein secretion pathway components; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.462 |
| RnhB | PTH_1707 | PTH_1708 | PTH_1707 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Predicted endonuclease; Distantly related to archaeal holliday junction resolvase; Belongs to the UPF0102 family. | 0.817 |
| RnhB | TatA | PTH_1708 | PTH_1709 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Sec-independent protein secretion pathway components; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.450 |