| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BisC-2 | TatA | PTH_1712 | PTH_1709 | Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Sec-independent protein secretion pathway components; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.609 |
| BisC-2 | TatC | PTH_1712 | PTH_1710 | Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.681 |
| GlpG | TatA | PTH_2662 | PTH_1709 | Uncharacterized membrane protein; Homolog of Drosophila rhomboid. | Sec-independent protein secretion pathway components; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.749 |
| GlpG | TatA-2 | PTH_2662 | PTH_1715 | Uncharacterized membrane protein; Homolog of Drosophila rhomboid. | Sec-independent protein secretion pathway components. | 0.749 |
| PilT | SecD | PTH_1135 | PTH_1035 | Tfp pilus assembly protein; Pilus retraction ATPase PilT. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.664 |
| PilT | SecF | PTH_1135 | PTH_1036 | Tfp pilus assembly protein; Pilus retraction ATPase PilT. | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.648 |
| PilT | TatA | PTH_1135 | PTH_1709 | Tfp pilus assembly protein; Pilus retraction ATPase PilT. | Sec-independent protein secretion pathway components; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.696 |
| PilT | TatA-2 | PTH_1135 | PTH_1715 | Tfp pilus assembly protein; Pilus retraction ATPase PilT. | Sec-independent protein secretion pathway components. | 0.696 |
| PilT | TatC | PTH_1135 | PTH_1710 | Tfp pilus assembly protein; Pilus retraction ATPase PilT. | Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.660 |
| PilT | secE | PTH_1135 | PTH_0304 | Tfp pilus assembly protein; Pilus retraction ATPase PilT. | Hypothetical membrane protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.648 |
| PilT-2 | SecD | PTH_1146 | PTH_1035 | Tfp pilus assembly protein, pilus retraction ATPase PilT. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.664 |
| PilT-2 | SecF | PTH_1146 | PTH_1036 | Tfp pilus assembly protein, pilus retraction ATPase PilT. | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.648 |
| PilT-2 | TatA | PTH_1146 | PTH_1709 | Tfp pilus assembly protein, pilus retraction ATPase PilT. | Sec-independent protein secretion pathway components; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.696 |
| PilT-2 | TatA-2 | PTH_1146 | PTH_1715 | Tfp pilus assembly protein, pilus retraction ATPase PilT. | Sec-independent protein secretion pathway components. | 0.696 |
| PilT-2 | TatC | PTH_1146 | PTH_1710 | Tfp pilus assembly protein, pilus retraction ATPase PilT. | Sec-independent protein secretion pathway component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.660 |
| PilT-2 | secE | PTH_1146 | PTH_0304 | Tfp pilus assembly protein, pilus retraction ATPase PilT. | Hypothetical membrane protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.648 |
| SecD | PilT | PTH_1035 | PTH_1135 | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Tfp pilus assembly protein; Pilus retraction ATPase PilT. | 0.664 |
| SecD | PilT-2 | PTH_1035 | PTH_1146 | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Tfp pilus assembly protein, pilus retraction ATPase PilT. | 0.664 |
| SecD | SecF | PTH_1035 | PTH_1036 | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.999 |
| SecD | TatA | PTH_1035 | PTH_1709 | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Sec-independent protein secretion pathway components; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.828 |