Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTH_1778Membrane signaling protein; Containing NtrB (COG3852), signal transduction histidine kinase. (546 aa)    
Predicted Functional Partners:
CheY
FOG: CheY-like receiver.
 
 0.979
CheY-3
FOG: CheY-like receiver.
  
  
  0.972
CitB
Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
  0.934
CheR
Methylase of chemotaxis methyl-accepting proteins.
    
 0.790
OmpR
Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 
 0.688
OmpR-7
Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 
 0.687
OmpR-6
Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 
 0.660
OmpR-2
Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 
 0.627
OmpR-8
Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 
 0.625
OmpR-3
Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 
 0.613
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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