| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FtsI-4 | Lgt | PTH_1867 | PTH_0965 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | Prolipoprotein diacylglyceryltransferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.450 |
| FtsI-4 | MurE-2 | PTH_1867 | PTH_1866 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.956 |
| FtsI-4 | MurF | PTH_1867 | PTH_1865 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.953 |
| FtsI-4 | ftsL | PTH_1867 | PTH_1868 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | Hypothetical membrane protein; Essential cell division protein; Belongs to the FtsL family. | 0.891 |
| FtsI-4 | mraZ | PTH_1867 | PTH_1870 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | Uncharacterized protein conserved in bacteria; Belongs to the MraZ family. | 0.797 |
| FtsI-4 | rsmH | PTH_1867 | PTH_1869 | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | Predicted S-adenosylmethionine-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.868 |
| Lgt | FtsI-4 | PTH_0965 | PTH_1867 | Prolipoprotein diacylglyceryltransferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | 0.450 |
| Lgt | rsmH | PTH_0965 | PTH_1869 | Prolipoprotein diacylglyceryltransferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Predicted S-adenosylmethionine-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.793 |
| MurE-2 | FtsI-4 | PTH_1866 | PTH_1867 | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | 0.956 |
| MurE-2 | MurF | PTH_1866 | PTH_1865 | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.997 |
| MurE-2 | ftsL | PTH_1866 | PTH_1868 | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Hypothetical membrane protein; Essential cell division protein; Belongs to the FtsL family. | 0.596 |
| MurE-2 | mraZ | PTH_1866 | PTH_1870 | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Uncharacterized protein conserved in bacteria; Belongs to the MraZ family. | 0.727 |
| MurE-2 | rsmH | PTH_1866 | PTH_1869 | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Predicted S-adenosylmethionine-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.825 |
| MurF | FtsI-4 | PTH_1865 | PTH_1867 | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Cell division protein FtsI/penicillin-binding protein 2; With 2x PASTA domain. | 0.953 |
| MurF | MurE-2 | PTH_1865 | PTH_1866 | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.997 |
| MurF | ftsL | PTH_1865 | PTH_1868 | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Hypothetical membrane protein; Essential cell division protein; Belongs to the FtsL family. | 0.606 |
| MurF | mraZ | PTH_1865 | PTH_1870 | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Uncharacterized protein conserved in bacteria; Belongs to the MraZ family. | 0.740 |
| MurF | rsmH | PTH_1865 | PTH_1869 | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Predicted S-adenosylmethionine-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.806 |
| RpsF | RpsI | PTH_2892 | PTH_0357 | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.999 |
| RpsF | RpsO | PTH_2892 | PTH_1274 | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | Ribosomal protein S15P/S13E; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.999 |