STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_1873Hypothetical protein. (359 aa)    
Predicted Functional Partners:
MetF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.922
HIS2
Histidinol phosphatase and related hydrolases of the PHP family; Belongs to the PHP hydrolase family. HisK subfamily.
       0.795
CdhD
CO dehydrogenase/acetyl-CoA synthase delta subunit; Corrinoid Fe-S protein.
 
   
 0.769
MetK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.768
CdhE
CO dehydrogenase/acetyl-CoA synthase gamma subunit; Corrinoid Fe-S protein.
  
   
 0.761
SAM1
S-adenosylhomocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
  
 0.726
PTH_1005
Hypothetical protein.
  
     0.692
MetH
Methionine synthase I; Containing cobalamin-binding domain.
 
  
 0.677
MIS1
Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
 
 
 0.665
PTH_2253
Predicted NADH:ubiquinone oxidoreductase.
  
     0.633
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.