Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTH_1944Collagenase and related proteases. (845 aa)    
Predicted Functional Partners:
PTH_1945
Uncharacterized conserved protein.
       0.844
POL4
DNA polymerase IV (family X) and COG1387 HIS2, histidinol phosphatase and related hydrolases of the PHP family.
       0.724
Mpg
3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family.
       0.613
NapF
Ferredoxin.
  
   0.568
PTH_2647
Hypothetical membrane protein; Containing partial NuoG (COG1034), NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G).
   
   0.542
PTH_1948
Uncharacterized protein conserved in bacteria; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
     
 0.459
PTH_1941
Hypothetical membrane protein.
       0.425
FeoB-2
Fe2+ transport system protein B.
       0.425
FeoA-2
Fe2+ transport system protein A.
       0.425
PTH_0881
Uncharacterized protein conserved in bacteria; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
   
    0.401
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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