Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTH_1958Hypothetical protein. (106 aa)    
Predicted Functional Partners:
CbiM-2
ABC-type Co2+ transport system, permease component.
 
  
  0.987
CbiQ-4
ABC-type cobalt transport system, permease component CbiQ and related transporters.
 
 
 0.968
CbiO-5
ABC-type cobalt transport system, ATPase component; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
 
 
 0.947
CbiM
ABC-type Co2+ transport system, permease component; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
 
  
  0.925
cbiD
Cobalamin biosynthesis protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
 
 0.906
CbiQ-2
ABC-type cobalt transport system, permease component CbiQ and related transporters.
  
 
 0.890
CobH
Precorrin isomerase; Containing CbiX domain.
  
  
 0.660
PTH_0952
precorrin-6B methylase 1,2; Containing COG2241 and COG2242.
  
  
 0.642
PTH_0956
precorrin-3B methylase and precorrin-6x reductase; COG1010, CobJ and COG2099, CobK.
  
  
 0.596
CbiQ-3
ABC-type cobalt transport system, permease component CbiQ and related transporters.
 
  
 0.547
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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