Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SleB-2Cell wall hydrolyses; Involved in spore germination. (221 aa)    
Predicted Functional Partners:
PTH_2852
Hypothetical membrane protein.
 
  
 0.864
PTH_1229
Hypothetical protein; Containing partial FabH (COG0332), 3-oxoacyl-[acyl-carrier-protein].
  
  
 0.720
gpr
peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.696
PTH_0638
Hypothetical protein; Containing AbrB regulators of stationary/sporulation gene expression (COG2002) domain.
  
   
 0.687
PTH_1228
Hypothetical membrane protein.
  
  
 0.678
AbrB-2
Regulators of stationary/sporulation gene expression.
  
   
 0.663
PTH_0185
Hypothetical membrane protein.
 
   
 0.655
PTH_2800
Hypothetical protein.
  
  
 0.652
PTH_1847
peptidase_U4, Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
   
 0.642
PTH_1168
Hypothetical membrane protein.
  
   
 0.576
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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