STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HypBNi2+-binding GTPase; Involved in regulation of expression and maturation of urease and hydrogenase. (225 aa)    
Predicted Functional Partners:
HypD
Hydrogenase maturation factor.
 
  
 0.960
HypC
Hydrogenase maturation factor.
 
  
 0.901
HybF
Zn finger protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.897
HypF
Hydrogenase maturation factor.
 
   
 0.885
HypE
Hydrogenase maturation factor.
 
  
 0.885
HyaB
Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.850
HyaA
Ni,Fe-hydrogenase I small subunit.
 
  
 0.846
HyaD
Ni,Fe-hydrogenase maturation factor.
 
  
 0.808
PTH_1816
Uncharacterized conserved protein.
  
    0.738
PTH_0028
Containing COG4624, iron only hydrogenase large subunit, C-terminal domain; COG2000, predicted Fe-S protein; and PAS domain.
  
    0.731
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.