Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SIR2-2NAD-dependent protein deacetylases; SIR2 family. (323 aa)    
Predicted Functional Partners:
PTH_2442
Hypothetical protein.
   
   0.769
PTH_2020
Hypothetical protein.
       0.507
RpoC
DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.484
GdhA
Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.467
AcuC
Deacetylases; Including yeast histone deacetylase and acetoin utilization protein.
    
 0.463
AcuC-2
Deacetylases; Including yeast histone deacetylase and acetoin utilization protein.
    
 0.463
AcuC-3
Deacetylases; Including yeast histone deacetylase and acetoin utilization protein.
    
 0.463
PolA
DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.447
SbcD
DNA repair exonuclease.
   
   0.427
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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