Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTH_2126FOG: CBS domain. (211 aa)    
Predicted Functional Partners:
PTH_1319
Hypothetical protein; Containing partial COG3153, predicted acetyltransferase.
 
  
 0.695
guaA
Hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.651
PTH_2127
Hypothetical protein.
       0.496
PTH_2128
Hypothetical protein.
       0.480
PTH_2125
Hypothetical protein.
       0.478
AcuC
Deacetylases; Including yeast histone deacetylase and acetoin utilization protein.
  
  
 0.476
AcuC-2
Deacetylases; Including yeast histone deacetylase and acetoin utilization protein.
  
  
 0.476
AcuC-3
Deacetylases; Including yeast histone deacetylase and acetoin utilization protein.
  
  
 0.476
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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