Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTH_2132Hypothetical protein. (47 aa)    
Predicted Functional Partners:
SdhB
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 
 0.725
SdhB-2
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 
 0.725
AcpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.715
NapF
Ferredoxin.
  
  
 0.670
IlvD
Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.653
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.653
NifS
Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 
 0.615
NifS-2
Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 
 0.615
IscU
NifU homolog; Involved in Fe-S cluster formation.
  
 
 0.608
IscU-2
NifU homolog; Involved in Fe-S cluster formation.
  
 
 0.608
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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