Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PolA-2DNA polymerase I - 3'-5' exonuclease and polymerase domains. (751 aa)    
Predicted Functional Partners:
FliS
Flagellin-specific chaperone FliS.
  
 
 0.971
PTH_2157
Hypothetical protein.
       0.844
NrdD-2
Oxygen-sensitive ribonucleoside-triphosphate reductase.
 
  
 0.796
FlgK
Flagellar hook-associated protein.
  
  
 0.780
FliA
DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.
 
 
 0.774
PTH_2113
Hypothetical protein.
  
  
 0.774
PTH_2156
Holliday junction resolvase; Archaeal type.
  
    0.773
PTH_2288
Hypothetical protein.
 
 
 0.766
FliD
Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.764
FliL
Flagellar basal body-associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
  
 0.761
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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