| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GyrB | PTH_0142 | PTH_0005 | PTH_0142 | Type IIA topoisomerase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | 0.579 |
| GyrB | Tar-3 | PTH_0005 | PTH_2202 | Type IIA topoisomerase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Methyl-accepting chemotaxis protein. | 0.545 |
| PTH_0142 | GyrB | PTH_0142 | PTH_0005 | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | Type IIA topoisomerase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.579 |
| PTH_0142 | Tar-3 | PTH_0142 | PTH_2202 | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | Methyl-accepting chemotaxis protein. | 0.553 |
| PTH_2204 | Tar-3 | PTH_2204 | PTH_2202 | Hypothetical protein. | Methyl-accepting chemotaxis protein. | 0.549 |
| PTH_2204 | UspA-3 | PTH_2204 | PTH_2203 | Hypothetical protein. | Universal stress protein UspA and related nucleotide-binding proteins. | 0.732 |
| Tar-3 | GyrB | PTH_2202 | PTH_0005 | Methyl-accepting chemotaxis protein. | Type IIA topoisomerase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.545 |
| Tar-3 | PTH_0142 | PTH_2202 | PTH_0142 | Methyl-accepting chemotaxis protein. | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | 0.553 |
| Tar-3 | PTH_2204 | PTH_2202 | PTH_2204 | Methyl-accepting chemotaxis protein. | Hypothetical protein. | 0.549 |
| Tar-3 | UspA-3 | PTH_2202 | PTH_2203 | Methyl-accepting chemotaxis protein. | Universal stress protein UspA and related nucleotide-binding proteins. | 0.578 |
| UspA-3 | PTH_2204 | PTH_2203 | PTH_2204 | Universal stress protein UspA and related nucleotide-binding proteins. | Hypothetical protein. | 0.732 |
| UspA-3 | Tar-3 | PTH_2203 | PTH_2202 | Universal stress protein UspA and related nucleotide-binding proteins. | Methyl-accepting chemotaxis protein. | 0.578 |
