Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PTH_2277Hypothetical protein. (49 aa)    
Predicted Functional Partners:
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
 
  
 0.673
PTH_0377
Predicted metal-dependent membrane protease.
  
  
 0.671
NfnB
Nitroreductase.
  
  
 0.509
NfnB-2
Nitroreductase.
  
  
 0.509
NfnB-3
Nitroreductase.
  
  
 0.509
NfnB-4
Nitroreductase.
  
  
 0.509
PTH_2276
Hypothetical protein; Containing SpoIIAA (COG1366), anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
       0.495
LivF-3
ABC-type branched-chain amino acid transport systems, ATPase component.
       0.458
LivG-3
ABC-type branched-chain amino acid transport systems, ATPase component.
       0.458
TagG
ABC-type polysaccharide/polyol phosphate export systems, permease component.
  
  
 0.439
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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