STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tdh-3Threonine dehydrogenase and related Zn-dependent dehydrogenases. (369 aa)    
Predicted Functional Partners:
PTH_1584
Putative aldehyde/alcohol dehydrogenase; Containing PutA (COG1012), NAD-dependent aldehyde dehydrogenases and EutG (COG1454) alcohol dehydrogenase class IV; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.925
PTH_0267
Hypothetical protein; Containing NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family (COG1902) and TrxB, thioredoxin reductase (COG0492).
 
 
 0.585
NemA-2
NADH:flavin oxidoreductases; Containing TrxB (COG0492), thioredoxin reductase domain.
 
 
 0.577
PTH_2407
Hypothetical membrane protein; Containing GloB (COG0491), Zn-dependent hydrolases, including glyoxylases and partial LytE (COG1388), FOG: LysM repeat.
 
 
 
 0.561
LeuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 
 0.547
LeuC-2
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 
 0.547
PykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.540
EutG
Alcohol dehydrogenase; Class IV.
  
 
 0.492
EutG-2
Alcohol dehydrogenase; Class IV.
  
 
 0.492
EutG-3
Alcohol dehydrogenase; Class IV.
  
 
 0.492
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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