Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PrpD-2Uncharacterized protein involved in propionate catabolism. (462 aa)    
Predicted Functional Partners:
Sbm
methylmalonyl-CoA mutase, C-terminal domain/subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
     
 0.625
MmcH
acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
  
    0.579
CitE
Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.575
PTH_1494
Hypothetical protein.
  
    0.433
Acs
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
 
  
 0.432
glmE
Glutamate mutase epsilon subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
       0.424
PTH_1495
Conserved hypothetical protein; With DUF1446.
  
    0.417
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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