Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MesJ-2Predicted ATPase; PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. (250 aa)    
Predicted Functional Partners:
SIR2-3
NAD-dependent protein deacetylases; SIR2 family.
       0.725
PTH
peptidyl-tRNA hydrolase.
  
  
 0.625
PTH_0252
ATP-utilizing enzymes; PP-loop superfamily.
 
    0.602
PTH_2666
Hypothetical protein.
       0.547
Sun
tRNA and rRNA cytosine-C5-methylases; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.505
PTH_2629
ATP-utilizing enzymes of the PP-loop superfamily.
 
    0.486
UvrB
Helicase subunit of the DNA excision repair complex.
  
    0.469
PTH_0117
Hypothetical protein; Containing SrmB, superfamily II DNA and RNA helicases (COG0513) and TRCF domain.
  
    0.469
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
  
 0.424
PTH_0914
Hyporthetical protein; Containing COG0327 and COG3323 domain; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.404
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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