STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_2674HD-GYP domain. (377 aa)    
Predicted Functional Partners:
PTH_2615
Hypothetical replicative DNA helicase; Containing FhlA (COG2203), FOG: GAF domain and partial COG2206, HD-GYP domain.
  
     0.694
PTH_2673
Hypothetical protein.
       0.605
PTH_1727
Hypothetical signaling protein; Containing FOG:GGDEF domain (COG2199) and ResE, FOG: HAMP domain (COG2770).
 
 0.575
PTH_2757
Hypothetical membrane protein; Containing FOG (COG2199): GGDEF domain and FhlA (COG2203), FOG: GAF domain.
 
 0.530
PTH_0666
Hypothetical signaling protein; Containing Rtn (COG2200), FOG: EAL domain.
  
  
 0.495
PTH_0546
Hypothetical protein; Containing COG2206, HD-GYP domain and FhlA (COG2203), FOG: GAF domain.
 
 
0.416
PTH_0744
Hypothetical protein; Containing FtsA resion (actin-like ATPase involved in cell division, COG0849).
  
 
   0.415
PTH_1663
Hypothetical protein; Containing COG2202, AtoS, FOG: PAS/PAC domain, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain, and HDc, Metal dependent phosphohydrolases with conserved 'HD' motif.
 
 
0.402
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
Server load: low (22%) [HD]