Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTH_2741uracil-DNA glycosylase. (202 aa)    
Predicted Functional Partners:
Gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.718
PTH_0742
Inactive homolog of metal-dependent proteases; Putative molecular chaperone.
  
    0.603
PTH_1174
Hypothetical protein; Containing COG5016 and COG0511 domains.
  
    0.583
PTH_2742
Predicted RNA binding protein.
       0.525
PTH_2743
Hypothetical serine protease; Containing PDZ domain.
  
    0.494
FlgC
Flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
    
   0.489
PolA
DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.468
MmcL
Transcarboxylase, 5S subunit; Pyruvate/oxaloacetate carboxyltransferase.
   
    0.447
ComEC-2
Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region.
      
 0.442
Prc-2
Periplasmic protease; Belongs to the peptidase S41A family.
  
    0.423
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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