Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Prc-2Periplasmic protease; Belongs to the peptidase S41A family. (385 aa)    
Predicted Functional Partners:
FtsX
Cell division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
     0.669
PTH_2745
Membrane-bound metallopeptidase.
 
 
 
 0.621
PTH_0026
Hypothetical protein.
  
 
 0.594
FtsE
Predicted ATPase; Part of the ABC transporter FtsEX involved in cellular division.
 
     0.587
PTH_1120
Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases.
  
 
 0.552
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
     
 0.549
PTH_1261
Predicted membrane-associated Zn-dependent protease 1.
 
  
 0.532
PTH_2743
Hypothetical serine protease; Containing PDZ domain.
       0.494
PTH_1174
Hypothetical protein; Containing COG5016 and COG0511 domains.
  
    0.443
PTH_2741
uracil-DNA glycosylase.
  
    0.423
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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