STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ComFCPredicted amidophosphoribosyltransferases. (246 aa)    
Predicted Functional Partners:
Smf
Predicted Rossmann fold nucleotide-binding protein; Involved in DNA uptake.
 
 
 0.897
ComEC-2
Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region.
 
  
 0.890
PTH_1690
Predicted ATPase; With chaperone activity.
 
  
 0.797
PTH_0257
Hypothetical protein.
  
  
 0.773
PTH_2757
Hypothetical membrane protein; Containing FOG (COG2199): GGDEF domain and FhlA (COG2203), FOG: GAF domain.
  
    0.757
FlgC
Flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
   
   0.749
TyrA
Prephenate dehydrogenase.
   
  
 0.694
Apt
Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.636
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
  
 0.629
RadC
DNA repair proteins; Belongs to the UPF0758 family.
  
    0.621
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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