Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ManB-4Phosphomannomutase. (470 aa)    
Predicted Functional Partners:
RnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
    
 0.793
GalU-2
UDP-glucose pyrophosphorylase.
    
 0.790
GlgP
Glucan phosphorylase.
  
 
 0.689
dacA
Uncharacterized conserved protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.671
mcsB
Argininekinase; Catalyzes the specific phosphorylation of arginine residues in proteins.
 
 
    0.666
PTH_1236
Hypothetical protein; Containing COG0517and COG0617 domains; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
   
 0.655
GlgB
1,4-alpha-glucan branching enzyme.
  
  
 0.651
PTH_2763
Hypothetical protein.
       0.551
PTH_2731
Hypothetical protein.
  
  
 0.503
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
  
 0.499
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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