Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TolCOuter membrane protein. (358 aa)    
Predicted Functional Partners:
PTH_2786
Hypothetical membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.937
AcrA-5
Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.924
PTH_2790
Hypothetical protein.
 
   
 0.886
AcrB-2
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.835
AcrB
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.825
PTH_0764
Hypothetical membrane protein.
     0.805
PTH_1829
Hypothetical protein.
  
 
 0.794
PTH_2798
Hypothetical serine protease; Containing Peptidase_S8, Subtilase family.
 
  
 0.791
AcrA
Membrane-fusion protein.
 
 
 0.750
EmrA
Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.745
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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