Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MreB-2Actin-like ATPase; Involved in cell morphogenesis. (343 aa)    
Predicted Functional Partners:
MreC
Cell shape-determining protein; Involved in formation and maintenance of cell shape.
 
 
 0.959
PTH_1295
Uncharacterized protein conserved in bacteria.
  
 
 0.857
FtsI
Cell division protein; FtsI/penicillin-binding protein 2.
 
 
 0.843
PTH_1933
Uncharacterized protein conserved in bacteria.
  
 
 0.825
FtsW
Bacterial cell division membrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.785
PTH_2234
Uncharacterized conserved protein; Containing a ferredoxin-like domain.
   
   0.762
FtsA
Actin-like ATPase; Involved in cell division.
   
 
 0.706
HipB-2
Predicted transcriptional regulator.
   
 
 0.683
FtsI-2
Cell division protein; FtsI/penicillin-binding protein 2.
 
 
 
 0.667
FtsZ
Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.655
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.