Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EmrAMultidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (357 aa)    
Predicted Functional Partners:
PTH_2803
ABC-type multidrug transport system, permease component.
 
  
 0.949
PTH_2804
ABC-type multidrug transport system, permease component.
 
  
 0.935
PTH_2802
Hypothetical protein; Containing partial CcmA (COG1131), ABC-type multidrug transport system, ATPase component.
 
  
 0.896
TolC
Outer membrane protein.
 
 
 0.745
PTH_1514
ABC-type multidrug transport system, permease component.
  
 0.668
SalY
ABC-type antimicrobial peptide transport system, permease component.
 
  
 0.640
SalY-2
ABC-type antimicrobial peptide transport system, permease component.
 
  
 0.638
AcrB-2
Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.524
CcmA-6
ABC-type multidrug transport system, ATPase component.
 
  
 0.518
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
  
 0.503
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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