Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTH_2805Hypothetical membrane protein; Containing 3 x S-layer homology (SLH) domain and partial COG4886, Leucine-rich repeat (LRR) protein. (1108 aa)    
Predicted Functional Partners:
PTH_0186
Hypothetical membrane protein; SLH, S-layer homology domain.
 
  
 0.709
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
 
  
 0.695
PTH_2496
Hypothetical membrane protein.
 
  
 0.611
PTH_2778
Hypothetical protein; Containing partial WcaK (COG2327), uncharacterized conserved protein.
 
     0.600
PTH_0168
Hypothetical membrane protein.
 
     0.570
PTH_2339
Hypothetical protein.
  
     0.520
PTH_2790
Hypothetical protein.
  
     0.504
PrfA
Protein chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
   
 0.501
PTH_0765
Hypothetical signaling protein; Containing TolB (COG0823), periplasmic component of the Tol biopolymer transport system.
 
     0.493
PTH_2788
Hypothetical protein.
 
     0.470
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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