Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PanFNa+/panthothenate symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (508 aa)    
Predicted Functional Partners:
PaaK-5
Coenzyme F390 synthetase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
     0.774
PutP
Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
     0.628
Lrp-3
Transcriptional regulator.
     
 0.588
Apt
Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.567
PutP-3
Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
     0.567
PTH_2846
Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
     0.565
PTH_2849
Aspartate/tyrosine/aromatic aminotransferase.
     
 0.556
PorG-5
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
 
     0.550
PrmA
Ribosomal protein L11 methylase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
      0.486
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
  
 0.476
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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