Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTH_2852Hypothetical membrane protein. (452 aa)    
Predicted Functional Partners:
PTH_2853
Hypothetical protein; Containing partial SleB (COG3773), cell wall hydrolyses involved in spore germination.
 
  
 0.975
SleB-2
Cell wall hydrolyses; Involved in spore germination.
 
  
 0.864
PTH_1847
peptidase_U4, Sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
   
 0.768
PTH_1838
Hypothetical membrane protein; Containing Spore_GerAC domain (pfam05504).
 
   
 0.741
SleB
Cell wall hydrolyses; Involved in spore germination.
 
  
 0.698
PTH_1839
Hypothetical membrane protein; Containing spore permease (pfam03845).
 
   
 0.687
PTH_1241
Uncharacterized conserved protein.
  
   
 0.659
PTH_0185
Hypothetical membrane protein.
 
   
 0.624
SleB-3
Cell wall hydrolyses involved in spore germination.
 
  
 0.623
PTH_1840
Hypothetical membrane protein; Containing GerA domain (pfam03323).
 
  
 0.619
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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