Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FabG-3Dehydrogenases with different specificities; Related to short-chain alcohol dehydrogenases. (254 aa)    
Predicted Functional Partners:
RpiB
Ribose 5-phosphate isomerase RpiB.
    
 0.822
Rpe
Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
   
 
 0.819
PTH_2895
Predicted metal-dependent hydrolase.
  
  
 0.770
SbcD
DNA repair exonuclease.
   
 
 0.734
FabD
(acyl-carrier-protein) S-malonyltransferase.
 
 0.693
PTH_2893
Hypothetical transporter; Containing partial AraJ (COG2814), arabinose efflux permease and partial UhpC (COG2271), sugar phosphate permease.
 
   
 0.692
CaiC-2
acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
 0.680
FabB
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.662
guaB
Hypothetical protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.638
PaaJ
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.632
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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