STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH55603.1Thioredoxin; Belongs to the thioredoxin family. (111 aa)    
Predicted Functional Partners:
SEH55595.1
Thioredoxin reductase (NADPH).
 0.999
SEH92884.1
Response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 0.969
SEH48211.1
Thioredoxin reductase.
  
 0.874
SEH74968.1
Thioredoxin reductase.
  
 0.874
SEH81624.1
Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.842
SEH73460.1
Thioredoxin reductase.
  
 0.836
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
  
 
 
 0.823
groL-2
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.818
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.815
SEH68149.1
Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.805
Your Current Organism:
Mycolicibacterium rutilum
NCBI taxonomy Id: 370526
Other names: CIP 109271, DSM 45405, JCM 16371, M. rutilum, Mycobacterium rutilum, Mycobacterium rutilum Hennessee et al. 2009, Mycobacterium sp. czh-107, Mycobacterium sp. czh-117, Mycobacterium sp. czh-132, Mycolicibacterium rutilum (Hennessee et al. 2009) Gupta et al. 2018, strain czh-117
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