STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH58000.13-hydroxyisobutyrate dehydrogenase. (285 aa)    
Predicted Functional Partners:
SEH58008.1
3-hydroxyisobutyrate dehydrogenase.
 
    
0.823
SEH58724.1
3-hydroxyisobutyrate dehydrogenase.
  
     0.761
SEH92959.1
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
     0.726
SEH58020.1
Hypothetical protein.
       0.572
SEH63720.1
Short chain enoyl-CoA hydratase.
   
 
 0.554
SEH57992.1
DNA-binding transcriptional regulator, HxlR family.
       0.552
SEH85731.1
Glycerate kinase; Belongs to the glycerate kinase type-1 family.
  
 
  0.494
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.457
SEH64232.1
Citrate synthase; Belongs to the citrate synthase family.
    
  0.457
SEH66561.1
propionyl-CoA synthetase.
    
  0.457
Your Current Organism:
Mycolicibacterium rutilum
NCBI taxonomy Id: 370526
Other names: CIP 109271, DSM 45405, JCM 16371, M. rutilum, Mycobacterium rutilum, Mycobacterium rutilum Hennessee et al. 2009, Mycobacterium sp. czh-107, Mycobacterium sp. czh-117, Mycobacterium sp. czh-132, Mycolicibacterium rutilum (Hennessee et al. 2009) Gupta et al. 2018, strain czh-117
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.