STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH74802.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)    
Predicted Functional Partners:
SEH72846.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.992
SEH75199.1
2-oxoglutarate dehydrogenase E2 component.
 
 0.989
SEH49815.1
Dihydrolipoamide dehydrogenase.
  
 
 0.978
SEH69601.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.977
SEH72832.1
Pyruvate dehydrogenase E1 component alpha subunit.
    
 0.932
SEH80452.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.920
SEH73221.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
 0.909
SEH86593.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.909
SEH86974.1
Acetolactate synthase, small subunit.
     
 0.908
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
   
 
 0.906
Your Current Organism:
Mycolicibacterium rutilum
NCBI taxonomy Id: 370526
Other names: CIP 109271, DSM 45405, JCM 16371, M. rutilum, Mycobacterium rutilum, Mycobacterium rutilum Hennessee et al. 2009, Mycobacterium sp. czh-107, Mycobacterium sp. czh-117, Mycobacterium sp. czh-132, Mycolicibacterium rutilum (Hennessee et al. 2009) Gupta et al. 2018, strain czh-117
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