Groups of genes that are frequently observed in each other's genomic neighborhood.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Fusion
Genes that are sometimes fused into single open reading frames.
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Databases
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BnaC06g06680D
Magnesium transporter; Magnesium transporter that may mediate the influx of magnesium; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family. (421 aa)
Predicted Functional Partners:
BnaC04g51860D
BnaC04g51860D protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
0.495
Your Current Organism:
Brassica napus
NCBI taxonomy Id: 3708 Other names: B. napus, oilseed rape, rape, rapeseeds
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
BnaC04g51860D
BnaC06g06680D
A0A078JEW1
A0A078HE36
BnaC04g51860D protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
Magnesium transporter; Magnesium transporter that may mediate the influx of magnesium; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
0.495
BnaC06g06680D
BnaC04g51860D
A0A078HE36
A0A078JEW1
Magnesium transporter; Magnesium transporter that may mediate the influx of magnesium; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
BnaC04g51860D protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
0.495
Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) disable highlightexplain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: