node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHF87346.1 | SHF97472.1 | SAMN05443663_101374 | SAMN05443663_101681 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.431 |
SHF87346.1 | SHG27169.1 | SAMN05443663_101374 | SAMN05443663_102386 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Dihydrolipoamide dehydrogenase. | 0.990 |
SHF87346.1 | SHG89652.1 | SAMN05443663_101374 | SAMN05443663_104225 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Signal transduction histidine kinase. | 0.566 |
SHF87346.1 | gcvH | SAMN05443663_101374 | SAMN05443663_101265 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.807 |
SHF87346.1 | gcvP | SAMN05443663_101374 | SAMN05443663_11335 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.879 |
SHF87346.1 | lipA | SAMN05443663_101374 | SAMN05443663_104223 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.526 |
SHF87346.1 | lipB | SAMN05443663_101374 | SAMN05443663_11234 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.538 |
SHF97472.1 | SHF87346.1 | SAMN05443663_101681 | SAMN05443663_101374 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.431 |
SHF97472.1 | SHG27169.1 | SAMN05443663_101681 | SAMN05443663_102386 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.987 |
SHF97472.1 | SHG89652.1 | SAMN05443663_101681 | SAMN05443663_104225 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Signal transduction histidine kinase. | 0.566 |
SHF97472.1 | gcvH | SAMN05443663_101681 | SAMN05443663_101265 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.807 |
SHF97472.1 | gcvP | SAMN05443663_101681 | SAMN05443663_11335 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.879 |
SHF97472.1 | lipA | SAMN05443663_101681 | SAMN05443663_104223 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.536 |
SHG16286.1 | lipA | SAMN05443663_10261 | SAMN05443663_104223 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.643 |
SHG16286.1 | lipB | SAMN05443663_10261 | SAMN05443663_11234 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase. | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.736 |
SHG27169.1 | SHF87346.1 | SAMN05443663_102386 | SAMN05443663_101374 | Dihydrolipoamide dehydrogenase. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.990 |
SHG27169.1 | SHF97472.1 | SAMN05443663_102386 | SAMN05443663_101681 | Dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.987 |
SHG27169.1 | gcvH | SAMN05443663_102386 | SAMN05443663_101265 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.906 |
SHG27169.1 | gcvP | SAMN05443663_102386 | SAMN05443663_11335 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.850 |
SHG27169.1 | lipA | SAMN05443663_102386 | SAMN05443663_104223 | Dihydrolipoamide dehydrogenase. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.549 |